Is obesity caused by more than eating too much and exercising too little?
A new article in the Proceedings of the National Academy of Sciences describes a genetic variation called ankyrin-B which may cause people to gain weight. This article by Damaris N. Lorezo and Vann Bennett demonstrates that ankyrin-B deficiency makes mice more likely to become obese with age or when fed a high-fat diet.
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Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency
Lorenzo, D. N., & Bennett, V. (2017). Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency. Proceedings of the National Academy of Sciences, 201708865.
Check out additional articles on genetics research in Dr. Charles Macri’s online Genetics Journal Club.