Publications


Contaminant Spot Check and Removal Assay (ContamSPOT) for Mass Spectrometry Analysis”. Smeriglio, N., Li, H., Mazli, A., Bendel, K., Hao, L., Analytical Chemistry, 96, 6, 2574-2581, 2024.


Multiomics Evaluation of Human iPSCs and iPSC-Derived Neurons”. Lee, G.B, Mazli, A. Hao, L., Journal of Proteome Research, 2024.

Multi-modal Proteomic Characterization of Lysosomal Function and Proteostasis in Progranulin-Deficient Neurons”. Hasan, S., Fernandopulle, M., Humble, S., Frankenfield, A., Li, H., Prestil, R., Johnson, K., Ryan, B., Wade-Martins, R., Ward, M. E., Hao, L., Molecular Neurodegeneration, 18, 87, 2023. (IF 15.8).




Protein Contaminants Matter: Building Universal Protein Contaminant Libraries for DDA & DIA Proteomics“. Frankenfield, A., Ni, J., Ahmed,M., Hao, L., Journal of Proteome Research, 21, 9, 2104–2113 2022. (Journal Front Cover)

Characterization of Neuronal Lysosome Interactome with Proximity Labeling Proteomics“. A. Frankenfield, A., Ni, J., Hao, L., Journal of Visualized Experiments, (184), e64132, 2022.


Integrated Proteomic and Metabolomic Analyses of the Mitochondrial Neurodegenerative Disease MELAS“. Li, H., Uittenbogaard, M., Navarro, R., Ahmed, M., Gropman, A., Chiaramello, A., Hao, L., Molecular Omics, 18, 196-205, 2022.

Thiol-Cleavable Biotin for Chemical and Enzymatic Biotinylation and Its Application to Mitochondrial TurboID Proteomics“. Li, H., Frankenfield, A.M., Houston, R., Sekine, S., and Hao, L., Journal of the American Society for Mass Spectrometry, 32, 9, 2358–2365, 2021. (Journal Front Cover)

Clinical Insights into Mitochondrial Neurodevelopmental and Neurodegenerative Disorders: Their Biosignatures from Mass Spectrometry-Based Metabolomics”. Li, H., Uittenbogaard, M., Hao, L., and Chiaramello, A., Metabolites, 11 (4), 233, 2021.

Development and Comparative Evaluation of Endolysosomal Proximity Labeling-based Proteomic Methods in Human iPSC-derived Neurons“. Frankenfield, A.M., Fernandopulle, M.S., Hasan, S., Ward, M.E. and Hao, L., Analytical Chemistry, 92 (23), 15437-15444, 2020.

Determining the Ethanol Concentrations in Ethyl Alcohol-Based Hand Sanitizers with Different Expiration Dates Using Fourier-Transform Infrared Spectroscopy (FT-IR)”. Shlafstein, M., Hannah, E., Hao, L., ChemRxiv, Preprint, Cambridge: Cambridge Open Engage; 2021.

Determining the Acetic Acid Concentration in White Vinegar: An At-Home Undergraduate Chemistry Experiment During the COVID-19 Pandemic.” Parel, P., Burnett, L., Geoffroy, M., Parel, J., Hao, L.. ChemRxiv, Preprint, Cambridge: Cambridge Open Engage; 2021.

Selected Publications prior to GW:

Sliter, D.A., Martinez, J., Hao, L., Chen, X., Sun, N., Fischer, T.D., Burman, J.L., Li, Y., Zhang, Z., Narendra, D.P. and Cai, H., Borsche, M., Klein, C., Youle., R.,”Parkin and PINK1 mitigate STING-induced inflammation“. Nature561(7722), 258-262. 2018.

Liao, Y.C., Fernandopulle, M.S., Wang, G., Choi, H., Hao, L., Drerup, C.M., Patel, R., Qamar, S., Nixon-Abell, J., Shen, Y. and Meadows, W., Vendruscolo, M., Knowles, T., Nelson, M., Czekalska, M.A., Musteikyte, G., Gachechiladze, M., Stepohen, C., Pasolli, A., Forrest, L., George-Hyslop, P., Lippincott-Schwartz, J., Ward, M., “RNA granules hitchhike on lysosomes for long-distance transport, using annexin A11 as a molecular tether.” Cell179(1), 147-164. 2019.

Lu, J., Zhong, X., Liu, H., Hao, L., Huang, C.T., Sherafat, M.A., Jones, J., Ayala, M., Li, L. and Zhang, S.C., “Generation of serotonin neurons from human pluripotent stem cells.” Nature Biotechnology34(1), 89. 2016.

Hao, L., Zhu, Y., Wei, P., Johnson, J., Buchberger, A., Frost, D., Kao, W.J. and Li, L., “Metandem: An online software tool for mass spectrometry-based isobaric labeling metabolomics“. Analytica Chimica Acta1088, 99-106, 2019.

Vargas, J. N. S., Wang, C., Bunker, E., Hao, L., Maric, D., Schiavo, G., … & Youle, R. J. “Spatiotemporal control of ULK1 activation by NDP52 and TBK1 during selective autophagy“. Molecular cell74(2), 347-362. 2019.

Hao, L., Wang, J., Page, D., Asthana, S., Zetterberg, H., Carlsson, C., … & Li, L. “Comparative Evaluation of MS-based Metabolomics Software and Its Application to Preclinical Alzheimer’s Disease“. Scientific Reports8, 2018.

Hao, L., Johnson, J., Lietz, C.B., Buchberger, A., Frost, D., Kao, W.J. and Li, L., “Mass defect-based N, N-dimethyl leucine labels for quantitative proteomics and amine metabolomics of pancreatic cancer cells“. Analytical Chemistry89(2), 1138-1146. 2017. (Journal Front Cover)

Liu, F., Ma, F., Wang, Y., Hao, L., Zeng, H., Jia, C., … & Chen, G. “PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis“. Nature cell biology19(11), 1358, 2017.

Thomas, S., Hao., L, Ricke, W., Li, L. “Biomarker Discovery in Mass Spectrometry-based Urinary Proteomics.” PROTEOMICS-Clinical Applications 10(4), 358, 2016. (Cover article)

Hao, L., Zhong, X., Greer, T., Ye, H., Li, L. “Relative Quantification of Amine- Containing Metabolites using Isobaric N,N-Dimethyl Leucine (DiLeu) Reagents via LC-ESI- MS/MS and CE-ESI-MS/MS.” Analyst, 140, 467, 2015.