Most central nervous system (CNS) disorders are currently incurable due to our limited understanding of disease mechanisms and the challenges of CNS drug development. MS-based techniques are widely applied to decipher the molecular mechanisms of neurological disorders and discover biomarkers and therapeutic targets for brain diseases.
JoVE is the first and only peer-reviewed scientific methods video journal, aimed at increasing the visibility and reproducibility of research, and the world-leading producer and provider of science videos.
This Method Collection will highlight recent advancements and methods in various MS techniques and MS-based analyses of diverse biomolecules, including but not limited to MS-based proteomics, peptidomics, metabolomics, lipidomics, MS-imaging, single-cell analysis, and biomarker discovery, with a special focus in studying the CNS. The goal is to provide video-based protocols and promote best practices in cutting-edge MS-based methodologies, assisting the researchers in the field to advance new technologies and deepen our understandings of the CNS. Abstract submission is now open for this special method collection.