Publications

1. Maiti, A., Buffalo, CZ., Saurabh, S., Montecinos-Franjola, F., Hachey, JS., Conlon, WJ., Tran, GN., Hassan, B., Walters, KJ., Drobizhev, M., Moerner, WE., Ghosh, P., Matsuo, H., Tsien, RY., Lin, JY., and Rodriguez, EA.*. 2023 “Structural and photophysical characterization of the small ultra-red fluorescent protein.” Nature Communications. 14(1): 4155. PMID: 37438348, PMCID: PMC10338489. *Corresponding author. https://doi.org/10.1038/s41467-023-39776-9 The author list contains two Chemistry Nobel Laureates.
2. Mattson, S., Tran, GN., and Rodriguez, EA.*. 2022 “Evolution of the small ultra-red fluorescent protein in bacteria.” In: Sharma, M. (eds) Fluorescent Proteins. Methods in Molecular Biology. Humana, New York, NY. 2564: 75-97. PMID: 36107338. *Corresponding author. https://doi.org/10.1007/978-1-0716-2667-2_4
3. Almogbil, HH., Montecinos-Franjola, F., Daszynski, C., Conlon, WJ., Hachey, JS., Corazzal, G., Rodriguez, EA., & Zderic, V.. 2022 “Therapeutic ultrasound for improving topical corneal delivery of macromolecules.” Translational Vision Science & Technology. 11(8): 23. PMID: 35998058. https://doi.org/10.1167/tvst.11.8.23
4. Mattson, S., Montecinos-Franjola, F., Csikai, N., Zitoun, L., & Rodriguez, EA.. 2021 “Compositions for and methods of improving directed evolution of biomolecules.” Application WO-2023114930-A1. Published June 22, 2023. https://app.dimensions.ai/details/patent/WO-2023114930-A1 The patent covers a faster-directed evolution of biomolecules that removes most molecular biology.
5. Machado, JH., Ting, R., Lin, JY., & Rodriguez, EA.*. 2021 “A self-labeling protein based on the small ultra-red fluorescent protein, smURFP.” RSC Chemical Biology. 2, 1221-1226. PMID: 34458834, PMCID: PMC8341759. *Corresponding author. https://doi.org/10.1039/D1CB00127B                                                                   Impact Science Infographic
6. Montecinos-Franjola, F., Lin, JY., & Rodriguez, EA.. 2020 “Fluorescent proteins for in vivo imaging, where’s the biliverdin?” Biochemical Society Transactions. 48: 2657–2667. PMID: 33196077. https://doi.org/10.1042/BST20200444
7. Mo, GCH., Posner, C., Rodriguez, EA., Sun, T., & Zhang, J.. 2020 “Rationally enhanced red fluorescent protein expands the utility of FRET biosensors.” Nature Communications. 11: 1848. PMID: 32296061, PMCID: PMC7160135. https://doi.org/10.1038/s41467-020-15687-x
8. An, F., Chen, N., Conlon, WJ., Hachey, JS., Xin, J., Aras, O., Rodriguez, EA.*, & Ting, R.*. 2020 “Small ultra-red fluorescent protein nanoparticles as exogenous probes for noninvasive tumor imaging in vivo.” International Journal of Biological Macromolecules. 153: 100-6. PMID: 32105698, PMCID: PMC7493049. *Co-corresponding authors. https://doi.org/10.1016/j.ijbiomac.2020.02.253
9. Rodriguez, EA.*, Tran, GN., Lin, JL, Ting, R., & Tsien, RY.. 2019 “Allophycocyanin alpha-subunit evolved labeling proteins (smURFPs).” US Patent.: US20180201655A1. *Corresponding author. https://patents.google.com/patent/US20180201655A1 https://pubchem.ncbi.nlm.nih.gov/patent/US2018201655
10. Sadegh, S., Yang, MH., Ferri, CGL., Thunemann, M., Saisain, PA., Wei, Z., Rodriguez, EA., Adams, SR., Kilic, K, Boas, DA., Sakadzic, S., Devor, A., & Fainman, Y.. 2019 “Efficient non-degenerate two-photon excitation for fluorescence microscopy.” Optics Express. 27(20): 28022-35. PMID: 31684560, PMCID: PMC6825618. https://doi.org/10.1364/oe.27.028022
11. Guo, H., Kommidi, H., Vedvyas, Y., McCloskey, JE., Zhang, J., Chen, N., Nurili, F., Wu, AP., Sayman, H., Akin, O., Rodriguez, EA., Aras, O., Jin, MM., & Ting, R.. 2019 “A fluorescent, [¹⁸F]-positron-emitting agent for imaging PMSA allows genetic reporting in adoptively-transferred, genetically-modified cells.” American Chemical Society Chemical Biology. 14(7): 1449-59. PMID: 31120734, PMCID: PMC6775626. https://doi.org/10.1021/acschembio.9b00160
12. Almogbil, H., Daszynski, C., Rodriguez, EA., Singh, T., Stepp, MA., & Zderic, V.. 2019 “Therapeutic ultrasound for improving the topical corneal delivery of macromolecules.” The Journal of the Acoustical Society of America. 145(3): https://doi.org/10.1121/1.5101867
13. Smith, M., Burgos, M., & McCoy, F.. 2019 Science of the Sea: A Hawai’i-Based Perspective of Oceanography. Chapter 5 Chemistry of the Ocean. Pueo Press. ISBN-10: 179843038X. https://www.amazon.com/Science-Sea-Hawaii-Based-Perspective-Oceanography/dp/179843038X EA. Rodriguez’s turtle image created with E. coli expressing CFP and mTangerine is featured in Ch. 5.
14. Wang, Y., An, FF., Chan, M., Friedman, B., Rodriguez, EA., Tsien, RY., Aras, O., & Ting, R.. 2017 “¹⁸F-positron-emitting/fluorescent labeled erythrocytes allow imaging of internal hemorrhage in murine intracranial hemorrhage model.” Journal of Cerebral Blood Flow and Metabolism. 37(3): 776-86. PMID: 28054494, PMCID: PMC5363488. https://doi.org/10.1177/0271678x16682510
    
15. Rodriguez, EA.*, Campbell*, RE., Lin, JY.*, Lin, MZ.*, Miyawaki, A.*, Palmer, AE.*, Shu, X.*, Zhang, J.*, & Tsien, RY.*. 2017 “The growing and glowing toolbox of fluorescent and photoactive proteins.” Trends in Biochemical Sciences. 42(2): 111-29. PMID: 27814948, PMCID: PMC5272834. *Co-corresponding authors. https://doi.org/10.1016/j.tibs.2016.09.010 This paper has been tweeted to >500,000 people. This paper is in the top 99^th percentile of all papers tracked by Altmetric. EA. Rodriguez designed the cover. Chosen as one of the Best of Trends 2017. Paper cited 353 times as of June 9, 2021.
16. Rodriguez, EA.*, Shaner, NC.*, Lin, MZ.*, & Campbell, RE.*. 2016 “Roger Y. Tsien (1952-2016).” Nature Methods. 13(11): 893. *Co-corresponding authors. https://doi.org/10.1038/nmeth.4044
17. Rodriguez, EA.*, Tran, GN., Gross, LA., Crisp, JC., Shu, XS., Lin, JY., & Tsien, RY.. 2016 “A far-red fluorescent protein evolved from a cyanobacterial phycobiliprotein.” Nature Methods. 13(9): 763-9. PMID: 27479328, PMCID: PMC5007177. *Corresponding author. https://doi.org/10.1038/nmeth.3935 This paper has been tweeted to >300,000 people. smURFP constructs have been requested >700 times in >25 countries from Addgene. smURFP has a Wikipedia page. This paper is in the top 99^th percentile of all papers tracked by Altmetric. EA. Rodriguez designed the cover. Dedicated to the memory of Roger Y. Tsien. Paper cited 125 times as of June 9, 2021.
18. Rodriguez, EA., Wang, Y., Crisp, JL., Vera, DR., Tsien, RY., & Ting, R.. 2016 “New dioxaborolane chemistry enables ¹⁸F-positron-emitting, fluorescent ¹⁸F-multimodality biomolecule generation from the solid phase.” Bioconjugate Chemistry. 27(5): 1390-9. PMID: 27064381, PMCID: PMC4916912. https://doi.org/10.1021/acs.bioconjchem.6b00164 The technology has been tested in humans without toxicity or death. Fully funded companies are started in New York, New York to test the technology in the FDA clinical trials.
19. Li, Y., Barber, Q., Paproski, RJ., Enterina, JR., Rodriguez, EA., Tsien, RY., Campbell, RE., & Zemp, RJ.. 2016 “Engineering a near-infrared dark chromoprotein optimized for photoacoustic imaging.” SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016. 97081Z. https://doi.org/10.1117/12.2209150
20. Rodriguez, EA., Ngo,, Palida, SF., Adams, SR., Mackey, MR., Ramachandra, R., Ellisman, MH., & Tsien, RY.. 2015 “New molecular tools for light and electron microscopy.” Microscopy and Microanalysis. 21(Suppl 3): 1-2. https://doi.org/10.1017/s143192761500080x
21. Pantoja, R., Rodriguez, EA., Dibas, MI., Dougherty, DA., & Lester, HA.. 2009 “Single-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptors.” Biophysical Journal. 96(1): 226-37. PMID: 19134478, PMCID: PMC2710013. https://doi.org/10.1016/j.bpj.2008.09.034
22. Rodriguez, EA., Lester, HA., & Dougherty, DA.. 2007 “Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 1: Minimizing misacylation.” RNA. 13: 1703-14. PMID: 17698638, PMCID: PMC1986802. https://doi.org/10.1261/rna.666807
23. Rodriguez, EA., Lester, HA., & Dougherty, DA.. 2007 “Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 2: Evaluating suppression efficiency.” RNA. 13: 1715-22. PMID: 17698637, PMCID: PMC1986817. https://doi.org/10.1261/rna.667607
24. Rodriguez, EA., Lester, HA., & Dougherty, DA.. 2006 “In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression.” Direct submission to the Proceedings of the National Academy of Sciences of the United States of America [Hard Track]. 103(23): 8650-5. PMID: 16728509, PMCID: PMC1482635. https://doi.org/10.1073/pnas.0510817103
25. Samson, AO., Chill, JH., Rodriguez, E., Scherf, T., & Anglister, J.. 2001 “NMR mapping and secondary structure determination of the major acetylcholine receptor α-subunit determinant interacting with α-bungarotoxin.” 40(18): 5464-73. PMID: 11331011. https://doi.org/10.1021/bi0022689

All publications can be found at the following links:

https://www.ncbi.nlm.nih.gov/sites/myncbi/erik.rodriguez.1/bibliography/40787605/public/

http://orcid.org/0000-0001-9143-2535

https://scholar.google.com/citations?user=RdwYA90AAAAJ&hl=en