Skip to content

Leah Steckler, MD

January 15th, 2018

As we enter the New Year, it is hard to forget the many lessons of 2017, a year that will likely be remembered for several reasons, among them the seemingly never-ending natural disasters. This past September, Hurricane Maria was the most powerful to hit Puerto Rico in almost 100 years (1).

Hearing stories from providers, like that from Dr. Zorrilla’s account published in November in the New England Journal of Medicine (NEJM) gives us a glimpse into what it might be like to practice in a far less than ideal environment (1). Importantly, Dr. Zorilla, an obstetrician-gynecologist, notes that neither she nor her staff had training in disaster management, and that it would have been difficult to predict and prepare for the level of devastation that Puerto Rico experienced. When a hospital is involved in a natural disaster, it is still vital to provide good quality patient care with few interruptions despite limited resources.

Accessing clean water was one of the challenges described in the NEJM article. According to the World Health Organization, 15% of patients worldwide develop an infection during a hospital stay, and this occurs with increased frequency in low-income countries with limited access to clean water (2).

Keeping track of any acquired illnesses, and accounting for chronic problems, also proves to be difficult without access to electronic medical records. Having a good contingency plan, formulating a strong back-up system, preparing for other simultaneous technologic emergencies, and planning for post-outage processing, makes a difference (3). Training staff ahead of time to know how to use a paper system may also be prudent. These concerns also extend to research. Having back ups for data and specimens can prevent mother nature from destroying valuable contributions to the scientific community, as happened to many in the wake of Hurricane Katrina in 2005 (4).

Without clean water or reliable electricity, treating patients in need of emergency surgery required urgent transport to the United States (1). Maintaining an adequate supply of sterile surgical equipment for those who stayed on the island also proved challenging because Dr. Zorilla’s team was unable to autoclave instruments.

An unexpected consequence of Hurricane Maria was its effect on drug manufacturers. Baxter pharmaceuticals and Johnson and Johnson both have factories in Puerto Rico and provide numerous medications and additives to the United States (5). This has forced hospital administrations and providers to find alternative medications and new suppliers.

Puerto Rico certainly experienced devastation beyond what most can imagine. The lessons gained from last year’s numerous natural disasters have challenged practitioners to be better clinicians, improve emergency preparedness, maximize ingenuity, and use teamwork to overcome innumerable obstacles.

What will you do to protect your hospital and emergency department when the next natural disaster strikes?

Resources:

  1. Zorilla, CD. The View from Puerto Rico — Hurricane Maria and Its Aftermath. N Engl J Med. 2017 Nov 9;377(19):1801-1803.
  2. Drinking Water. World Health Organization. July 2017. Available online at: http://www.who.int/mediacentre/factsheets/fs391/en/
  3. Minghella, Linda. Be Prepared: Lessons from an Extended Outage of a Hospital’s EHR System. 2013. Available online 3 Jan 2018 at: https://www.healthcare-informatics.com/article/be-prepared-lessons-extended-outage-hospital-s-ehr-system?page=2
  4. Singer, E. Research losses surface in hurricane Katrina's aftermath. Nat Med. 2005 Oct;11(10):1015.
  5. Thomas, K. U.S. Hospitals Wrestle With Shortages of Drug Supplies Made in Puerto Rico. Available online 23 October 2017: https://www.nytimes.com/2017/10/23/health/puerto-rico-hurricane-maria-drug-shortage.htm

Leah Steckler, MD is an Emergency Medicine Resident at The George Washington University Hospital

 

Leah Steckler, MD

November 20th, 2017

According to the Centers for Disease Control, opioids were involved in 33,091 deaths in 2015 and overdoses have increased four-fold since 1999, including both illicit and prescribed opioid medications (1). This dramatic increase in mortality has persisted despite prescribers writing fewer prescriptions for opioids in the past few years (2).  It is possible that fewer opioid prescriptions may lead to more patients experiencing withdrawal.  Current practice approaches in the emergency department (ED) tend to focus more on symptomatic treatment with anti-emetic and anti-diarrheal agents, and referral to rehabilitation services (3).  The standard of care does not currently include opioid agonist-antagonists, like buprenorphine, in the acute period for the management of these patients. The unpleasant effects of withdrawal undoubtedly contribute to opioid addiction. As such, improving pharmacologic methods to control withdrawal symptoms may provide another means of fighting this epidemic.

An article in Annals of Emergency Medicine by Love et al. (4) presents an emergency medicine-focused snapshot of a recent Cochrane Review assessing our current opioid withdrawal treatments (5). This Cochrane Review analyzed data from 27 studies comparing buprenorphine to tapered methadone, and studies comparing buprenorphine with clonidine (an alpha-2 adrenergic agonist used commonly to treat withdrawal symptoms).

Love and colleagues suggest that buprenorphine administration in the ED may be an appropriate intervention for opioid withdrawal. Fourteen of the studies compared buprenorphine and alpha-2 adrenergic agonists as pharmacologic withdrawal management. Using data extraction, subgroups were analyzed and the results showed that patients treated with buprenorphine had significantly lower withdrawal scores and greater number of days in treatment than patients treated with alpha 2-adrenergic medications. The authors concluded that the number of patients needed to treat with buprenorphine was four in order for one additional patient to reach withdrawal treatment (4) (Figure 1).

Figure 1: Buprenorphine versus alpha2-adrenergic agonists for acute opioid withdrawal (4)

Upon reviewing the above information, it is clear that limitations still exist with the use of buprenorphine to treat opioid withdrawal. Buprenorphine is not without risk and may cause dangerous adverse effects including hypotension, derangements in liver function, and respiratory depression (6). It is important that prescribers are comfortable with the evidence behind a medication, that they understand appropriate dosing regimens, and that the medications are safe for patients. Further, a provider cannot prescribe buprenorphine without taking an 8-hour course and receiving a certificate from the Drug Enforcement Agency (7). Additionally, this topic has not been well studied in the ED population, and there is always the risk of patients becoming addicted to the treatment for their addiction (8). Starting withdrawal treatment in the ED may help to bridge opioid users to outpatient treatment and contribute to our country’s mission to stave off future opioid abuse. Continued research on buprenorphine use in the ED is certainly worthwhile.

Resources:

  1. Drug Overdose Death Data. 2014-2015 Death Increases. CDC. Available from: https://www.cdc.gov/drugoverdose/data/statedeaths.html
  2. S. Prescribing Rate Maps. Total number and rate of opioid prescriptions dispensed, United States, 2006-2016. CDC. Available from: https://www.cdc.gov/drugoverdose/maps/rxrate-maps.html
  3. Tintinalli Burillo-Putze G, Miro O. Opioids. In: Tintinalli JE, Stapczynski J, Ma O, Yealy DM, Meckler GD, Cline DM. eds. Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e New York, NY: McGraw-Hill; 2016. http://accessmedicine.mhmedical.com.proxygw.wrlc.org/content.aspx?bookid=1658&sectionid=109414267. Accessed November 10, 2017.
  4. Love, J, Perrone, J, Nelson, L. Should Buprenorphine Be Administered to Patients with Opioid Withdrawal in the Emergency Department? Ann Emerg Med. Published online November
  5. Gowing L, Ali R, White JM, et al. Buprenorphine for managing opioid withdrawal. Cochrane Database Syst Rev. 2017;2:CD002025.
  6. Epocrates. Available from: https://online.epocrates.com/drugs/7468/Belbuca
  7. Buprenorphine Waiver Management. Available from: https://www.samhsa.gov/medication-assisted-treatment/buprenorphine-waiver-management
  8. Addicted to a Treatment for Addiction. New York Times. 2016. https://www.nytimes.com/2016/05/29/opinion/sunday/addicted-to-a-treatment-for-addiction.html

Leah Steckler, MD is an Emergency Medicine Resident at The George Washington University Hospital