GW-SOBS Student of the Month

OCTOBER

Anthony Laucevicius

(he/him/his)

Program: Cancer Biology

PI: Dr. Edward Seto

Why did you choose to pursue a PhD?

[AL] I am driven to pursue a Ph.D. in cancer biology by the profound impact that cancer has had on my life since childhood. Witnessing close friends and family members grapple with this disease has ignited a deep sense of purpose, I developed my passion for challenging scientific pursuits to contribute to cancer research. Growing up, I have always had an insatiable curiosity, eager to ask ‘why’ and explore the world around me. Pursuing answers propelled me toward diverse directions which has inspired me to embark on a Ph.D. journey where I can unravel the “whys” and contribute meaningfully to this critical field. Additionally, the complexity of cancer biology presents a formidable challenge that I am eager to tackle head-on to make a lasting difference in the lives of those affected by cancer.

Tell us about your project!

[AL] My research project focuses on investigating the function of HDAC11 inhibitors in chemoresistance High Grade Serous Ovarian Cancer (HGSOC). HGSOC is one of the most aggressive and deadly gynecological diseases affecting women in the United States. Patients face significant challenges in terms of effective treatment. The development of acquired chemoresistance, complex signaling pathways, and the immunosuppressive tumor microenvironment present significant obstacles in managing the disease thereby limiting patients’ options for alternative treatments. My main objective is to advance our understanding of how HDAC11 inhibitors play a role in chemoresistant ovarian cancer cells and the associated anti-tumor response that underlie the development and progression of ovarian cancer and may provide a novel blueprint for possibilities of innovative therapeutic strategies.

What are some skills (scientific or non-scientific) you have gained while in the program?

[AL] Becoming a part of this program as a deaf scientist has marked a significant period of personal growth for me. I encountered various challenges along the way, both in my own education and in enlightening others about how we can collaborate effectively throughout my journey as a deaf Ph.D. student. Overcoming imposter syndrome was particularly challenging, especially in the context of history disadvantage in the deaf community. I had to show that deafness is just a genetic condition that doesn’t impede my personal and professional life. With time and currently in my fourth year, I gradually learned to set more realistic expectations, give myself greater flexibility, and noticed improvements in my later experiences. Moreover, I have acquired the skill of reaching out for collaboration, engaging in discussion with principal investigators, and recognizing that you don’t have to do everything alone. This ability was something I had to learn.

What do you like to do outside of lab?

[AL] My favorite hobbies are cycling, fitness training, and playing basketball and tennis. I’m actively participating in the tennis league, which provides me the opportunity to meet new people! Washington D.C. has numerous scenic trails that I enjoy cycling on and uncover hidden gems in this city that I never knew existed, even though I have lived here for eight years. There are so many hidden spots to explore!

What are your favorite things to do in the DC/DMV area?

[AL] My favorite thing to do is to try as many of Washington D.C.’s restaurants as I can. This city has a wide variety of culinary specialties! Nevertheless, I must admit that, in comparison to American dishes, I find Mcdonald’s burgers more enjoyable 🙂

Any pets?

[AL] I have two dogs! German shepherd and Golden Retriever named Luna and Ivy. They have been a remarkable addition to my life, teaching me valuable lessons about life, love and patience. They serve as a reminder that life is not about work; there are aspects where you can learn, love, and make a commitment beyond your professional endeavors!

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Thank you Anthony, for sharing!